glutamate receptor antagonists การใช้

• Current research is targeting glutamate receptor antagonists as potential treatments for schizophrenia.
• AMPA iGluRs modulate the secretion of insulin and glucagon in the pancreas, opening the possibility of treatment of diabetes via glutamate receptor antagonists.
• Recent studies have been performed that incorporate glutamate receptor antagonists and excitotoxic cascade disruptors in order to decrease stimulation of postsynaptic neurons, although these treatments are still undergoing active research.
• The afferents to this area areglutamatergic, or use glutamate as their primary neurotransmitter, although angiotensin II produces a similar response, and result in sypathoexcitation of the PVN . This was confirmed by the use of a glutamate receptor antagonist in the PVN, which inhibited this response as a result of the activation of the MnPn.